Early Heart Attacks and genetic variation

A slew of brief communications in Nature Genetics (before publication) discuss the impact of nine different genetic variants that are associated with early myocardial infarction (commonly referred to as a heart attack. The reports are from the myocardial infarction consortium and identified nine SNPs (three new and six previously identified SNPs associated with early heart attack. The three newly identified ones are: MRPS6-SLC5A3-KCNE2 on chromosome 21, PHACTR1 on chromosome 6, and WDR12 on chromosome 2. They did not find any association with Copy Number Variants (CNVs).

Links
Science Daily article

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

New susceptibility locus for coronary artery disease on chromosome 3q22.3

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease